Strain-dependent inhibition of Clostridioides difficile by commensal Clostridia encoding the bile acid inducible (bai) operon
A. D. Reed, M. A. Nethery, A. Stewart, R. Barrangou, C. M. Theriot
This study shows that commensal Clostridia with the bai operon inhibit C. difficile growth in a strain-dependent manner through bile acid conversion, but C. difficile outcompetes them in co-culture.
bioRxiv · Jan 22, 2020Microbiology