Author

M. A. Outram

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:protein structure· 3 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:plant (other)· 1

Frequent Co-Authors

S. J. Williams· 4 shared D. J. Ericsson· 3 shared A. Smith· 2 shared D. A. Jones· 2 shared D. S. Yu· 2 shared J. Sperschneider· 2 shared L. Ma· 2 shared X. Sun· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersPlant Biology

S. J. Williams

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4 papers

Recent·Most cited

AvrSr27 is a zinc-bound effector with a modular structure important for immune recognition

M. A. Outram, J. Chen, S. Broderick, Z. Li, S. Aditya, N. Tasneem, T. Arndell, C. Blundell, D. J. Ericsson, M. Figueroa, J. Sperschneider, P. Dodds, S. J. Williams

The paper reports the crystal structure of AvrSr27, a Pgt effector, revealing its modular zinc-bound fold and its role in immune recognition by Sr27.

bioRxiv · Nov 21, 2023Plant Biology

The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies

D. S. Yu, M. A. Outram, A. Smith, C. L. McCombe, P. B. Khambalkar, S. A. Rima, X. Sun, L. Ma, D. J. Ericsson, D. A. Jones, S. J. Williams

This study identifies a new structural class of fungal effectors in Fusarium oxysporum f. sp. lycopersici using experimental and computational methods, revealing structural relationships and immune recognition mechanisms.

bioRxiv · Dec 14, 2021 · PreprintPlant Biology

Optimised production of disulfide-bonded fungal effectors in E. coli using CyDisCo and FunCyDisCo co-expression approaches

D. S. Yu, M. A. Outram, E. Crean, A. Smith, Y.-C. Sung, R. Darma, X. Sun, L. Ma, D. A. Jones, P. S. Solomon, S. J. Williams

This paper improves the production of disulfide-bonded fungal effectors in E. coli using CyDisCo and FunCyDisCo co-expression systems, enabling functional studies and crystallisation.

bioRxiv · Aug 31, 2021Biochemistry

The crystal structure of SnTox3 from the necrotrophic fungus Parastagonospora nodorum reveals a unique effector fold and insights into Kex2 protease processing of fungal effectors

M. A. Outram, Y.-C. Sung, D. Yu, B. Dagvadorj, S. Rima, D. Jones, D. J. Ericsson, J. Sperschneider, P. Solomon, B. Kobe, S. J. Williams

The paper determines the crystal structure of SnTox3, a fungal effector, revealing a novel β-barrel fold and showing that it is a pre-pro-protein processed by Kex2 protease.

bioRxiv · May 27, 2020Plant Biology