The chicken chorioallantoic membrane model for isolation of CRISPR/cas9-based HSV-1 mutant expressing tumor suppressor p53
M. Kelishadi, H. Shahsavarani, A. Tabarraei…·K. Azadmanesh
This paper uses the chicken chorioallantoic membrane model to isolate a CRISPR/Cas9-modified HSV-1 mutant expressing tumor suppressor p53, showing its potential for oncolytic virus development.