Author

M. A. Sorensen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Organism:E. coli· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

K. Gerdes· 2 shared N. Mitarai· 2 shared S. L. Svenningsen· 2 shared A. Harms· 1 shared B. Gummesson· 1 shared C. Fino· 1 shared D. E. Brodersen· 1 shared F. Bisiak· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

K. Gerdes

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin-antitoxin system

R. L. Baerentsen, S. V. Nielsen, R. B. Skjerning, J. Lyngso, F. Bisiak, J. S. Pedersen, K. Gerdes, M. A. Sorensen, D. E. Brodersen

The paper investigates the structural basis of kinase inhibition in the E. coli HipBST toxin-antitoxin system, showing how HipS inhibits HipT through active site insertion and how phosphorylation affects complex flexibility.

bioRxiv · Jan 28, 2022 · PreprintMicrobiology

Existence of log-phase Escherichia coli persisters and lasting memory of a starvation pulse

M. S. Svenningsen, S. L. Svenningsen, M. A. Sorensen, N. Mitarai

This study quantifies long-term killing dynamics of E. coli during antibiotic treatment and identifies a memory effect from carbon starvation.

bioRxiv · Sep 17, 2020 · PreprintMicrobiology

Distinct survival, growth lag, and ribosomal RNA degradation kinetics during long-term starvation for carbon or phosphate

Y. Himeoka, B. Gummesson, M. A. Sorensen, S. L. Svenningsen, N. Mitarai

This study compares ribosomal RNA degradation and survival kinetics in Escherichia coli under carbon and phosphate starvation, finding faster rRNA loss and longer lag times under phosphate starvation.

bioRxiv · Sep 4, 2020 · PreprintMicrobiology

Nasty Prophages and the Dynamics of Antibiotic-Tolerant Persister Cells

A. Harms, C. Fino, M. A. Sorensen, S. Semsey, K. Gerdes

This study reevaluates persister cell formation in E. coli by refining experimental methods to eliminate artifacts from prophages and culture conditions, confirming the role of (p)ppGpp and Lon but refuting TA modules.

mBio · Dec 29, 2017Peer-reviewedMicrobiology