Adipose triglyceride lipase promotes prostaglandin-dependent actin remodeling by regulating substrate release from lipid droplets
M. S. Giedt, J. M. Thomalla, M. R. Johnson, Z. W. Lai, T. L. Tootle, M. A. Welte
This study shows that ATGL regulates actin remodeling in Drosophila oogenesis by releasing arachidonic acid from lipid droplets to drive prostaglandin synthesis, essential for follicle development and fertility.
bioRxiv · Aug 2, 2021Cell Biology