Structurally Distributed Surface Sites Tune Allosteric Regulation
J. W. McCormick, M. A. X. Russo, S. Thompson, A. Blevins, K. A. Reynolds
The paper investigates how mutations affect allosteric regulation by analyzing the impact of 1548 DHFR single mutations on allostery using a high-throughput assay.
bioRxiv · Mar 11, 2021Biophysics