Author

J. W. McCormick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:CITE-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. G. Wise· 2 shared P. D. Vogel· 2 shared A. Blevins· 1 shared C. A. Follit· 1 shared C. Park· 1 shared G. Chen· 1 shared K. A. Reynolds· 1 shared L. A. McCormick· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

J. G. Wise

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Computationally accelerated identification of P-glycoprotein inhibitors

L. A. McCormick, J. W. McCormick, C. Park, C. A. Follit, J. G. Wise, P. D. Vogel

This study identifies nine novel P-gp inhibitors using a computationally accelerated drug discovery pipeline, showing they reverse multidrug resistance in cancer cells with minimal toxicity to non-cancerous cells.

bioRxiv · Mar 5, 2024 · PreprintCancer Biology

Structurally Distributed Surface Sites Tune Allosteric Regulation

J. W. McCormick, M. A. X. Russo, S. Thompson, A. Blevins, K. A. Reynolds

The paper investigates how mutations affect allosteric regulation by analyzing the impact of 1548 DHFR single mutations on allostery using a high-throughput assay.

bioRxiv · Mar 11, 2021Biophysics

Transport of Alzheimer's Associated Amyloid-β Catalyzed by P-glycoprotein

J. W. McCormick, L. Ammerman, G. Chen, P. D. Vogel, J. G. Wise

This study shows P-glycoprotein actively transports amyloid-β proteins, suggesting a role in Alzheimer's disease progression.

bioRxiv · Oct 22, 2020Biochemistry