Author

M. B. Mumphrey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. CIESLIK· 2 shared M. Raghavan· 2 shared A. Chinnaiyan· 1 shared A. I. NESVIZHSKII· 1 shared A. J. ZAITOUNA· 1 shared A. KAUR· 1 shared A. Parolia· 1 shared A. SURNILLA· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersImmunology

M. CIESLIK

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mass spectrometric profiling of HLA-B44 peptidomes provides evidence for tapasin-mediated tryptophan editing

A. KAUR, A. SURNILLA, A. J. ZAITOUNA, B. VENKATESHA, M. B. MUMPHREY, I. L. GRIGOROVA, M. CIESLIK, M. CARRINGTON, A. I. NESVIZHSKII, M. Raghavan

The paper compares HLA-B44 peptidomes with and without tapasin to show tapasin influences C-terminal tryptophan residues and peptide binding affinity.

bioRxiv · Feb 26, 2023Immunology

Distinct mutational processes shape selection of MHC class I and class II mutations across primary and metastatic tumors

M. B. Mumphrey, N. Hosseini, A. Parolia, J. Geng, W. Zou, M. Raghavan, A. Chinnaiyan, M. Cieslik

The paper identifies distinct mutational processes in MHC class I and II genes across primary and metastatic tumors, showing positive selection for mutations disrupting immune interfaces and linking them to immune checkpoint inhibitor response.

bioRxiv · Jan 22, 2023Cancer Biology

OptiFit: an improved method for fitting amplicon sequences to existing OTUs

K. L. Sovacool, S. L. Westcott, M. B. Mumphrey, G. A. Dotson, P. D. Schloss

OptiFit improves OTU assignment by considering all reference-query sequence pairs, achieving quality similar to de novo methods while maintaining consistency across datasets.

bioRxiv · Nov 9, 2021Microbiology