Chemical genetics of AGC-kinases reveals shared targets of Ypk1, Protein Kinase A and Sch9
M. Plank, M. Perepelkina, M. Müller, S. Vaga, X. Zou, M. Berti, J. Saarbach, S. Haesendonckx, N. Winssinger, R. Aebersold, R. Loewith
The paper identifies shared targets of Ypk1, PKA, and Sch9 by comparing phospho-proteomes under chemical inhibition, revealing Ypk1's role in phosphorylating and activating Nth1.
bioRxiv · Sep 4, 2019Cell Biology