Structural basis of CBP/p300 recruitment by the microphthalmia-associated transcription factor
A. D. Brown, K. L. Vergunst, M. Branch, C. M. Blair, D. J. Dupre, G. S. Baillie, D. N. Langelaan
This study identifies the structural basis of MITF's interaction with CBP/p300 TAZ domains, revealing an acidic motif essential for transcriptional activity and showing that E1A can inhibit this interaction.
bioRxiv · Aug 28, 2022Biochemistry