Author

D. J. Dupre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:proteomics· 1

Frequent Co-Authors

A. D. Brown· 2 shared A. M. Tomko· 2 shared D. N. Langelaan· 2 shared E. G. Whynot· 2 shared C. Cranstone· 1 shared C. M. Blair· 1 shared G. S. Baillie· 1 shared K. L. Vergunst· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

A. D. Brown

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

β-catenin interacts with the TAZ1 and TAZ2 domains of CBP/p300 to activate gene transcription

C. Cranstone, A. D. Brown, D. J. Dupre, D. N. Langelaan

This study identifies the interaction between β-catenin's C-terminal domain and CBP/p300's TAZ1/TAZ2 domains, revealing key residues critical for gene activation in Wnt/β-catenin signaling.

bioRxiv · Aug 30, 2022Biochemistry

Structural basis of CBP/p300 recruitment by the microphthalmia-associated transcription factor

A. D. Brown, K. L. Vergunst, M. Branch, C. M. Blair, D. J. Dupre, G. S. Baillie, D. N. Langelaan

This study identifies the structural basis of MITF's interaction with CBP/p300 TAZ domains, revealing an acidic motif essential for transcriptional activity and showing that E1A can inhibit this interaction.

bioRxiv · Aug 28, 2022Biochemistry

Anti-cancer potential of cannabis terpenes in a taxol-resistant model of breast cancer

A. M. Tomko, E. G. Whynot, L. F. O'Leary, D. J. Dupre

This study evaluates the anti-cancer effects of cannabis terpenes in chemotherapy-resistant breast cancer models, finding that some terpenes and their combinations with cannabinoids and flavonoids show cytotoxicity and apoptosis induction.

bioRxiv · Oct 8, 2021Cancer Biology

Anti-cancer properties of cannabidiol and Δ9-tetrahydrocannabinol and potential synergistic effects with gemcitabine, cisplatin and other cannabinoids in bladder cancer

A. M. Tomko, E. G. Whynot, D. J. Dupre

This study investigates the anti-tumor effects of cannabinoids like cannabidiol and Δ9-tetrahydrocannabinol on bladder cancer cells and their potential synergistic effects with chemotherapeutics.

bioRxiv · Mar 25, 2021 · PreprintCancer Biology