Akt/PKB enhances non-canonical Wnt signals by compartmentalizing β-Catenin
N. Aznar, N. Sun, Y. Dunkel, J. Ear, M. Buschman, P. Ghosh
This study shows that Akt/PKB enhances non-canonical Wnt signals by phosphorylating Daple, which compartmentalizes β-catenin to cell-cell contact sites, suppressing colony growth.
bioRxiv · Jun 13, 2017Cell Biology