Inhibition of mitochondrial respiration impairs nutrient consumption and metabolite transport in human retinal pigment epithelium
R. Zhang, A. L. Engel, Y. Wang, B. Li, W. Shen, M. C. Gillies, J. R. Chao, J. Du
This study shows that inhibiting mitochondrial respiration in RPE cells alters intracellular and extracellular metabolites, revealing a metabolic signature of mitochondrial dysfunction.
bioRxiv · May 11, 2020Biochemistry