Author

M. C. Harrison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 5 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 6 Research Focus:chromatin & epigenetic regulation· 4 Organism:multiple species· 3 Research Focus:cell type annotation· 2 Approach:comparative / phylogenetic analysis· 2 Research Focus:development & morphogenesis· 2 Assay:DNA methylation· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

E. Bornberg-Bauer· 2 shared E. Dohmen· 2 shared A. Lopez-Ezquerra· 1 shared A. Mikhailova· 1 shared A. Moser· 1 shared A. Wada-Katsumata· 1 shared A.-K. Huylmans· 1 shared C. Greiner· 1 shared

Activity by Year

2015-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersEvolutionary Biology

E. Bornberg-Bauer

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Author profile →

6 papers

Recent·Most cited

Investigating the mechanisms of antibody binding to alpha-synuclein for the treatment of Parkinson's Disease

M. C. Harrison, P.-K. Lai

This study uses computational methods to analyze the binding of PRX002 to alpha-synuclein, showing strong binding affinity and conformational stability.

bioRxiv · Feb 27, 2024Biophysics

Major changes in domain arrangements are associated with the evolution of termite castes

A. Mikhailova, E. Dohmen, M. C. Harrison

The paper investigates domain rearrangements in termite proteomes to understand their role in the evolution of eusociality, finding novel arrangements linked to longevity and caste-specific functions.

bioRxiv · May 15, 2023 · PreprintEvolutionary Biology

Complex regulatory role of DNA methylation in caste- and age-specific expression of a termite.

M. C. Harrison, E. Dohmen, S. George, D. Sillam-Dusses, S. Seite, M. Vassuer-Cognet

This study investigates DNA methylation's role in caste- and age-specific gene expression in termite queens, finding significant methylation changes and links to alternative splicing in aging and fertility.

bioRxiv · Mar 8, 2022Evolutionary Biology

Gene co-expression network reveals highly conserved, well-regulated anti-ageing mechanisms in old ant queens.

M. C. Harrison, L. M. Jaimes Nino, M. Almeida Rodrigues, J. Ryll, T. Flatt, J. Oettler, E. Bornberg-Bauer

The paper analyzes gene co-expression networks in old ant queens to identify anti-ageing mechanisms and finds increased transcriptional regulation and strong purifying selection on key genes.

bioRxiv · Feb 14, 2021Evolutionary Biology

Hemimetabolous genomes reveal molecular basis of termite eusociality

M. C. Harrison, E. Jongepier, H. M. Robertson, N. Arning, T. Bitard-Feildel, H. Chao, C. P. Childers, H. Dinh, H. Doddapaneni, S. Dugan, J. Gowin, C. Greiner, Y. Han, H. Hu, D. S. T. Hughes, , E. Bornberg-Bauer

The paper compares genomes and transcriptomes of termites and cockroaches to identify molecular mechanisms underlying termite eusociality, finding parallels and differences with Hymenoptera.

bioRxiv · Nov 15, 2017Evolutionary Biology

Deleterious mutation accumulation in Arabidopsis thaliana pollen genes: a role for a recent relaxation of selection

M. C. Harrison, E. B. Mallon, D. Twell, R. L. Hammond

The paper compares selection strength on pollen and sporophytic genes in Arabidopsis thaliana, finding relaxed selection on pollen genes after the species became self-compatible, leading to more deleterious mutations.

bioRxiv · Nov 23, 2015Evolutionary Biology