Author

M. C. Heaphy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biochemistry· 1

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Approach:experimental assay· 1

Frequent Co-Authors

A. N. Loes· 1 shared G. D. Warren· 1 shared J. L. Harman· 1 shared K. J. Lampi· 1 shared M. J. Harms· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

A. N. Loes

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1 paper

Recent·Most cited

Evolution of multifunctionality through a pleiotropic substitution in the innate immune protein S100A9

J. L. Harman, A. N. Loes, G. D. Warren, M. C. Heaphy, K. J. Lampi, M. J. Harms

The paper shows how a single mutation in S100A9 affects its proinflammatory activity and proteolytic resistance while leaving S100A8/S100A9 antimicrobial activity unchanged, enabling multifunctionality in mammals.

bioRxiv · Dec 5, 2019Biochemistry