Antigen presentation dynamics shape the response to emergent variants like SARS-CoV-2 Omicron strain after multiple vaccinations with wild type strain
L. Yang, M. Van Beek, Z. Wang, F. Muecksch, M. Canis, T. Hatziioannou, P. D. Bieniasz, M. C. Nussenzweig, A. K. Chakraborty
The paper shows that antigen presentation dynamics after multiple vaccinations influence the immune response to SARS-CoV-2 Omicron by shaping B cell responses and antibody targeting of epitopes.
bioRxiv · Aug 24, 2022Immunology