Fructose Metabolism Contributes to the Warburg effect
B. HAN, L. Wang, J. Zhang, M. Wei, C. Rajani, R. Wei, J. Wang, H. Yang, M. Carbone, G. Xie, W. Zhou, w. jia
This study shows cancer cells use fructose metabolism to drive the Warburg effect by converting glucose to fructose via polyol pathways and exporting fructose to the tumor microenvironment.
bioRxiv · Jun 4, 2020Cancer Biology