Author

M. Castoldi

Primary ORCID profile (0000-0003-2484-936X · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

M. CastoldiiD1 paper · Düsseldorf University Hospital

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:statistical model· 3 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

T. Luedde· 3 shared L. R. Heij· 2 shared M. Paluschinski· 2 shared M. Vucur· 2 shared R. Pellegrino· 2 shared T. Longerich· 2 shared U. P. Neumann· 2 shared V. Buettner· 2 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCancer Biology

T. Luedde

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Author profile →

3 papers

Recent·Most cited

KIF23 regulation by miR-107 controls replicative tumor cell fitness in mouse and human hepatocellular carcinoma

M. Castoldi, S. Roy, C. Lohr, R. Pellegrino, M. Vucur, M. T. Singer, V. Buettner, M. A. Dille, L. R. Heij, L. Zender, U. P. Neumann, T. Longerich, C. Roderburg, T. Luedde

bioRxiv · Nov 20, 2023Cancer Biology

Differential modulation of miR-122 transcription by TGFbeta1/BMP6: implications for nonresolving inflammation and hepatocarcinogenesis

M. Paluschinski, C. Kordes, M. Vucur, V. Buettner, H. C. Xu, P. Shinde, P. A. Lang, T. Luedde, M. Castoldi

This study identifies miR-122 as a key regulator in inflammation-associated liver cancer, showing its differential modulation by TGFbeta1 and BMP6 and its link to chronic liver disease.

bioRxiv · Jun 30, 2023Cancer Biology

Uncovering novel roles of miR-122 in the pathophysiology of the liver: Potential interaction with NRF1 and E2F4 signaling

M. Paluschinski, J. Schira-Heinen, R. Pellegrino, L. R. Heij, J. Bednarsch, U. P. Neumann, T. Longerich, K. Stuehler, T. Luedde, M. Castoldi

This study identifies miR-122's role in liver disease by showing its antagonistic effects on NRF1 and E2F4 and its impact on proteins linked to malignancy.

bioRxiv · Jun 30, 2023Cancer Biology