Author

P. A. Lang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

H. C. Xu· 2 shared A. Ewen· 1 shared A. Waisman· 1 shared B. Becher· 1 shared B. Leiser· 1 shared C. Binsfeld· 1 shared C. Dostert· 1 shared C. Kordes· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

H. C. Xu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BATF controls IFN I production via DC-SCRIPT in plasmacytoid dendritic cells

S. Ali, R. Mann-Nüttel, M. Marson, B. Leiser, J. Hoffe, R. J. Dress, M. H. Bhuyan, P. Petzsch, K. Köhrer, H. C. Xu, P. A. Lang, S. Zhang, M. Chopin, S. L. Nutt, J. Alferink, S. Scheu

The paper shows BATF suppresses IFN I production in pDCs via DC-SCRIPT, revealing a negative feedback loop in antiviral immunity.

bioRxiv · Jan 11, 2024 · PreprintImmunology

A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation

L. Bonetti, V. Horkova, J. Longworth, L. Guerra, H. Kurniawan, D. G. Franchina, L. Soriano-Baguet, M. Grusdat, S. Spath, E. Koncina, A. Ewen, C. Binsfeld, C. Verscheuren, J.-J. Gerardy, T. Kobayashi, , D. Brenner

This study identifies a Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis that protects against intestinal inflammation by maintaining barrier integrity and preventing mortality from C. rodentium infection.

bioRxiv · Jul 6, 2023Immunology

Differential modulation of miR-122 transcription by TGFbeta1/BMP6: implications for nonresolving inflammation and hepatocarcinogenesis

M. Paluschinski, C. Kordes, M. Vucur, V. Buettner, H. C. Xu, P. Shinde, P. A. Lang, T. Luedde, M. Castoldi

This study identifies miR-122 as a key regulator in inflammation-associated liver cancer, showing its differential modulation by TGFbeta1 and BMP6 and its link to chronic liver disease.

bioRxiv · Jun 30, 2023Cancer Biology