DNA ligase I fidelity mediates the mutagenic ligation of pol β oxidized nucleotide insertion products and base excision repair intermediates with mismatches
P. Kamble, K. Hall, M. Chandak, Q. Tang, M. Caglayan
This study shows that DNA ligase I fidelity affects the mutagenic ligation of pol β insertion products and repair intermediates with mismatches, and how APTX and FEN1 remove 5-AMP blocks.
bioRxiv · Oct 30, 2020Biochemistry