Author

M. Couvillion

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Assay:cryo-EM· 1 Assay:metagenomics· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. Barrientos· 2 shared E. McShane· 2 shared I. C. Soto· 2 shared J. C. Moran· 2 shared L. S. Churchman· 2 shared A. Amunts· 1 shared A. R. Baxter-Koenigs· 1 shared B. M. Smalec· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersBiochemistry

A. Barrientos

Mutual co-authors in cluster

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3 papers

Recent·Most cited

A kinetic dichotomy between mitochondrial and nuclear gene expression drives OXPHOS biogenesis

E. McShane, M. Couvillion, R. Ietswaart, G. Prakash, B. M. Smalec, I. Soto, A. R. Baxter-Koenigs, K. Choquet, L. S. Churchman

The paper quantifies differences in nuclear and mitochondrial gene expression kinetics and identifies regulatory mechanisms underlying OXPHOS biogenesis.

bioRxiv · Feb 9, 2023Cell Biology

Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome

V. Singh, J. C. Moran, Y. Itoh, I. C. Soto, F. Fontanesi, M. Couvillion, M. Huynen, S. Churchman, A. Barrientos, A. Amunts

The paper determines the cryo-EM structure of LRPPRC-SLIRP complex with mRNA and mitoribosome, showing its role in mRNA delivery and translation regulation.

bioRxiv · Jun 20, 2022Biochemistry

Balanced mitochondrial and cytosolic translatomes underlie the biogenesis of human respiratory complexes

I. C. Soto, M. Couvillion, E. McShane, K. G. Hansen, J. C. Moran, A. Barrientos, L. S. Churchman

The paper investigates how human cells balance mitochondrial and cytosolic translatomes to coordinate OXPHOS complex biogenesis and maintains proteostasis through LRPPRC.

bioRxiv · May 31, 2021Cell Biology