Author

M. Huynen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:metagenomics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Amunts· 1 shared A. Barrientos· 1 shared A. Boleij· 1 shared A. Cabrera-Orefice· 1 shared A. J. H. Cremers· 1 shared A. van Heijst· 1 shared B. E. Dutilh· 1 shared B. van Dijk· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Amunts

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Parallel evolution and enhanced virulence upon in vivo passage of an RNA virus in Drosophila melanogaster

O. M. Lezcano, L. Fuhrmann, G. Ramakrishnan, N. Beerenwinkel, M. Huynen, R. P. van Rij

This study shows that RNA virus evolution under host immune pressure leads to parallel mutations in a specific viral protein, increasing virulence and replication efficiency across different host genotypes.

bioRxiv · Jul 21, 2023 · PreprintMicrobiology

Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome

V. Singh, J. C. Moran, Y. Itoh, I. C. Soto, F. Fontanesi, M. Couvillion, M. Huynen, S. Churchman, A. Barrientos, A. Amunts

The paper determines the cryo-EM structure of LRPPRC-SLIRP complex with mRNA and mitoribosome, showing its role in mRNA delivery and translation regulation.

bioRxiv · Jun 20, 2022Biochemistry

Nutrition or nature: disentangling the complex forces shaping prokaryote pan-genomes

D. R. Garza, F. A. B. von Meijenfeldt, B. van Dijk, A. Boleij, M. Huynen, B. E. Dutilh

The paper disentangles the forces shaping prokaryote pan-genomes by simulating metabolic reaction loss in different environments and identifying reactions constrained by nutrition or nature.

bioRxiv · Dec 14, 2020 · PreprintEvolutionary Biology

Composition and stage dynamics of mitochondrial complexes in Plasmodium falciparum

F. Evers, A. Cabrera-Orefice, D. M. Elurbe, M. Kea-te Lindert, S. D. Boltryk, T. S. Voss, M. Huynen, U. Brandt, T. W. A. Kooij

This study uses complexome profiling to analyze mitochondrial protein complexes in Plasmodium falciparum across different life stages, revealing stage-specific composition and functional shifts.

bioRxiv · Oct 5, 2020Microbiology

Surveillance-embedded genomic outbreak resolution of methicillin-susceptible Staphylococcus aureus in a neonatal intensive care unit

A. J. H. Cremers, J. Coolen, C. Bleeker-Rovers, N. van der Geest-Blankert, D. Haverkate, H. Hendriks, S. Henriet, M. Huynen, E. Kolwijck, D. Liem, W. Melchers, J. Rossen, J. Zoll, A. van Heijst, J. Hopman, H. Wertheim

The paper uses whole-genome sequencing to resolve MSSA outbreaks in a NICU, revealing more accurate transmission chains than traditional methods.

bioRxiv · Apr 13, 2019Microbiology