A mouse-adapted SARS-CoV-2 model for the evaluation of COVID-19 medical countermeasures
K. H. Dinnon, S. R. Leist, A. Schafer, C. E. Edwards, D. R. Martinez, S. A. Montgomery, A. West, B. L. Yount, Y. J. Hou, L. E. Adams, K. L. Gully, A. J. Brown, E. Huang, M. D. Bryant, I. C. Choong, , R. S. Baric
This paper develops a mouse-adapted SARS-CoV-2 model to evaluate medical countermeasures, showing age-related disease severity and the efficacy of IFN lambda-1a.
bioRxiv · May 6, 2020Microbiology