Author

M. D. Cain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2

Frequent Co-Authors

R. S. Klein· 2 shared X. Jiang· 2 shared C. Sun· 1 shared H. Salimi· 1 shared J. S. Hou· 1 shared N. R. Klein· 1 shared R. Roth· 1 shared W. B. Klimstra· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

R. S. Klein

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2 papers

Recent·Most cited

Post-exposure intranasal IFNα suppresses replication and neuroinvasion of Venezualen Equine Encephalitis virus within olfactory sensory neurons

R. S. Klein, M. D. Cain, N. R. Klein, X. Jiang

This study shows that intranasal IFNα treatment suppresses VEEV replication and neuroinvasion in olfactory sensory neurons, improving survival and delaying encephalitis onset in mice.

Journal of Neuroinflammation · Jan 17, 2024Peer-reviewedImmunology

Encephalitic alphaviruses exploit caveolae-mediated transcytosis at the blood-brain barrier for CNS entry

R. S. Klein, H. Salimi, M. D. Cain, X. Jiang, R. Roth, W. Beatty, C. Sun, W. B. Klimstra, J. S. Hou

This study shows alphaviruses use caveolae-mediated transcytosis across the blood-brain barrier to enter the CNS, and IFN restricts this process.

bioRxiv · Oct 16, 2019 · PreprintMicrobiology