Author

M. D. W. Tyner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Organism:non-human primate· 1 Assay:proteomics· 1

Frequent Co-Authors

A. B. F. Barletta· 1 shared A. Molina-Cruz· 1 shared A. Pan· 1 shared C. Barillas-Mury· 1 shared C. Fung· 1 shared E. R. Gerrick· 1 shared F. M. Gomes· 1 shared G. E. Canepa· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. B. F. Barletta

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Author profile →

2 papers

Recent·Most cited

Tuft cells mediate commensal remodeling of the small intestinal antimicrobial landscape

C. Fung, L. M. Fraser, G. M. Barron, M. B. Gologorsky, S. N. Atkinson, E. R. Gerrick, M. Hayward, J. Ziegelbauer, J. A. Li, K. F. Nico, M. D. W. Tyner, L. B. DeSchepper, A. Pan, N. H. Salzman, M. R. Howitt

This study shows that succinate from commensal protists activates tuft cells, leading to changes in antimicrobial peptides and microbiota composition in the small intestine.

bioRxiv · Oct 24, 2022Microbiology

Proliferation of DBLOX Peroxidase-Expressing Oenocytes Maintains Innate Immune Memory in Primed Mosquitoes

F. M. Gomes, M. D. W. Tyner, A. B. F. Barletta, L. Yenkoidiok-Douti, G. E. Canepa, A. Molina-Cruz, C. Barillas-Mury

The paper identifies DBLOX peroxidase-expressing oenocytes as critical for maintaining innate immune memory in Plasmodium-infected mosquitoes through histone acetylation.

bioRxiv · Sep 9, 2020 · PreprintImmunology