Author

M. Esposito

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Lujambio· 1 shared C. Zhang· 1 shared D. Pal· 1 shared D. Zeltsman· 1 shared G. D. Vrla· 1 shared G. Gionchetta· 1 shared G. Hannon· 1 shared G. Moreno-Hagelsieb· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Lujambio

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Disentangling abiotic and biotic effects of treated wastewater on stream biofilm resistomes enables the discovery of a new planctomycete beta-lactamase

M. Attrah, M. R. Schaerer, M. Esposito, G. Gionchetta, H. Buergmann, P. N. L. Lens, K. Fenner, J. van de Vossenberg, S. L. Robinson

This study investigates the effects of treated wastewater on stream biofilm resistomes, identifying a new planctomycete beta-lactamase that is functionally active despite low sequence similarity to known ARGs.

bioRxiv · Nov 20, 2023Microbiology

Non-synonymous to synonymous substitutions suggest that orthologs tend to keep their functions, while paralogs are a source of functional novelty

J. M. Escorcia-Rodriguez, M. Esposito, J. A. Freyre-Gonzalez, G. Moreno-Hagelsieb

The paper compares dN/dS ratios of orthologs and paralogs to assess functional divergence, finding orthologs more functionally stable than paralogs.

bioRxiv · Jun 22, 2022Evolutionary Biology

An epigenetic switch regulates the ontogeny of AXL positive/EGFR-TKI resistant cells by modulating miR-335 expression

R. Sordella, D. Pal, P. Safaric Tepes, T. Lindsted, I. Ibarra, A. Lujambio, V. Jimenez Sabinina, S. Senturk, M. Miller, N. Korimerla, J. Huang, L. Glassman, P. Lee, D. Zeltsman, K. Hyman, , G. Hannon

The paper identifies an epigenetic mechanism regulating AXL-positive/Erlotinib-resistant cells through miR-335 expression, suggesting combinatorial therapies for EGFR-mutated NSCLC.

bioRxiv · Jan 6, 2021Cancer Biology

Surface association induces cytotoxic alkyl-quinolones in Pseudomonas aeruginosa

G. D. Vrla, M. Esposito, C. Zhang, Y. Kang, M. R. Seyedsayamdost, Z. Gitai

This study identifies alkyl-quinolones as surface-induced cytotoxins in Pseudomonas aeruginosa and shows their role in virulence regulation.

bioRxiv · Jan 15, 2020 · PreprintMicrobiology