M. F. L. van 't Wout

This study investigates how pre-existing antibodies and memory T cell help influence the dynamics of recall germinal centers, showing that pre-existing antibodies suppress antigen binding while memory T cells enable B cells to access GCs despite low antigen binding.

The paper investigates how soluble MAC (sMAC) is formed during bacterial infections, finding that MAC-resistant bacteria convert C5 into C5b more efficiently and release sMAC, which can lyse bystander erythrocytes.