Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance
M. F. Pech, L. E. Fong, J. E. Villalta, L. J. G. Chan, S. Kharbanda, J. J. O'Brien, F. E. McAllister, A. J. Firestone, C. H. Jan, J. Settleman
The paper identifies DCAF15 as a target for enhancing NK cell-mediated cancer cell clearance through CRISPR screens and functional analysis in leukemia cells.
bioRxiv · Jul 20, 2019Cancer Biology