Development and applications of a CRISPR activation system for facile genetic overexpression in Candida albicans
N. C. Gervais, A. A. La Bella, L. F. Wensing, J. Sharma, V. Acquaviva, M. Best, R. O. Cadena Lopez, M. Fogal, D. Uthayakumar, A. Chavez, F. Santiago-Tirado, A. L. Flores-Mireles, R. S. Shapiro
This paper develops a CRISPR activation system for genetic overexpression in Candida albicans and demonstrates its ability to drive high-level gene expression and identify novel phenotypes.
bioRxiv · Aug 15, 2022Microbiology