Author

M. G. Lawrence

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

G. P. Risbridger· 2 shared R. A. Taylor· 2 shared A. Bakshi· 1 shared A. Clark· 1 shared A. G. Bert· 1 shared A. R. Hanson· 1 shared A. Ryan· 1 shared A. Zoubeidi· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

G. P. Risbridger

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2 papers

Recent·Most cited

Defining focal neuroendocrine differentiation as a transcriptionally distinct form of prostate cancer pathology characterized by the expression of androgen receptors

R. Quezada Urban, S. Keerthikumar, A. Clark, H. Wang, B. Phipson, A. Bakshi, A. Ryan, H. J. Thorne, R. A. Taylor, M. G. Lawrence, G. P. Risbridger, R. Toivanen, D. L. Goode

This study uses single-cell RNA sequencing to show that focal neuroendocrine differentiation (Focal NED) in prostate cancer is transcriptionally distinct, characterized by androgen receptor expression and unique transcriptional sub-populations.

bioRxiv · Mar 17, 2024 · PreprintCancer Biology

MicroRNA-194 promotes lineage plasticity in advanced prostate cancer

R. C. Fernandes, J. Toubia, S. Townley, A. R. Hanson, B. K. Dredge, K. A. Pillman, A. G. Bert, R. Iggo, R. Das, MURAL investigators, D. Obinata, S. Sandhu, G. P. Risbridger, R. A. Taylor, M. G. Lawrence, , L. Selth

This study identifies miR-194 as a regulator of lineage plasticity in prostate cancer by targeting FOXA1 and promoting transdifferentiation to a neuroendocrine-like state.

bioRxiv · Sep 12, 2019 · PreprintCancer Biology