A. Bakshi

Defining focal neuroendocrine differentiation as a transcriptionally distinct form of prostate cancer pathology characterized by the expression of androgen receptors

This study uses single-cell RNA sequencing to show that focal neuroendocrine differentiation (Focal NED) in prostate cancer is transcriptionally distinct, characterized by androgen receptor expression and unique transcriptional sub-populations.

Cytoplasmic divisions without nuclei

The paper shows that cytoplasmic divisions can occur without nuclei in fruit fly embryos, autonomously of the cell cycle, and are used to extrude delayed nuclei.

Ethylene-triggered subcellular trafficking of CTR1 enhances the response to ethylene gas

The paper shows ethylene causes CTR1 to move from the endoplasmic reticulum to the nucleus, stabilizing EIN3 and enhancing ethylene response in dark-grown seedlings.

Ribosomal Protein Large subunit RPL6 modulates salt tolerance in rice

This study shows that overexpressing RPL6 in rice improves salt tolerance by enhancing physiological responses and increasing seed yield under salt stress.

Gain of function mutagenesis through activation tagging identifies XPB2 and SEN1 helicase genes as potential targets for drought stress tolerance in rice

Target of Rapamycin: function in abiotic stress tolerance in Arabidopsis and its involvement in a possible cross-talk with ribosomal proteins

This paper shows that overexpressing TOR in Arabidopsis improves tolerance to osmotic and salt stress and links TOR to ribosomal protein regulation through phosphorylation of S6K1.

Neonatal genetics of gene expression reveal the origins of autoimmune and allergic disease risk

The paper identifies gene expression quantitative trait loci (eQTLs) in neonatal immune cells and links them to autoimmune and allergic disease risk through colocalisation and Mendelian randomisation.

The CURE for Culturing Fastidious Microbes

The paper describes a microbiology CURE program that uses a modified culturing protocol to isolate aquatic bacterioplankton, achieving similar success to standard lab settings.