ACSM1 and ACSM3 regulate prostate cancer fatty acid metabolism to promote tumour growth and constrain ferroptosis
R. Shrestha, Z. D. Nassar, A. R. Hanson, R. Iggo, S. L. Townley, J. Dehairs, C. Y. Mah, M. Helm, M. Alizadeh-Ghodsi, M. Pickering, M. J. Watt, L.-E. Quek, A. J. Hoy, W. D. Tilley, J. V. Swinnen, , L. A. Selth
This study identifies ACSM1 and ACSM3 as AR-regulated factors that promote prostate cancer growth by enhancing fatty acid metabolism and suppressing ferroptosis.
bioRxiv · Oct 13, 2022 · PreprintCancer Biology