M. G. Poirier

This study demonstrates the delivery of DNA origami nanorods into live cell nuclei using an antibody against RNA Polymerase II, showing structural integrity and sub-diffusive motion within the nucleus.

The paper introduces a DNA origami-based force sensor called NanoDyn that can be tuned to detect forces in the picoNewton range and demonstrates its reversibility and adjustability.

This paper develops a mesoscopic simulation model to study DNA origami folding, revealing hierarchical processes and kinetic differences between small and large structures.

The paper introduces MagicDNA 2.0, a tool for automated design of freeform 3D DNA nanostructures, validated through experimental fabrication of complex geometries.

This paper introduces a DNA origami-based method for steric communication between dynamic components, demonstrating signal transmission through thermal fluctuations and conformational regulation.

This paper introduces an electrostatic DNA caging method for nanoparticle modification, demonstrating its versatility in biosensing and material applications.

This study uses Monte Carlo simulations and experimental DNA origami rotors to show thermally reversible pattern formation in molecular rotor arrays, demonstrating order-disorder transitions and potential applications in nanomaterials.

This study shows how Cbf1's HLH region interacts with histones to slow nucleosome dissociation, enabling chromatin opening.

This study identifies that HIV-1 preintegration complex preferentially integrates viral DNA into nucleosomes with H3K36me3 modification and linker DNA.

This study examines how nucleosome composition affects the conformational dynamics and accessibility of the H3 histone tail in hexasomes and tetrasomes.

The paper develops a convergent hybrid phase ligation strategy for synthesizing large proteins, demonstrating its effectiveness with the 212-residue histone H1.2.