The paper introduces a DNA origami-based force sensor called NanoDyn that can be tuned to detect forces in the picoNewton range and demonstrates its reversibility and adjustability.

bioRxiv · Jun 26, 2023Bioengineering

DNA-caged Nanoparticles via Electrostatic Self-Assembly

E. Jergens, S. de Araujo Fernandes-Junior, Y. Cui, A. Robbins, C. Castro, M. G. Poirier, M. N. Gurcan, J. J. Otero, J. O. Winter

This paper introduces an electrostatic DNA caging method for nanoparticle modification, demonstrating its versatility in biosensing and material applications.

bioRxiv · Nov 7, 2022Bioengineering

Internet of Things Architecture for Cellular Biology

D. F. Parks, K. Voitiuk, J. Geng, M. A. T. Elliott, M. G. Keefe, E. A. Jung, A. Robbins, P. V. Baudin, V. T. Ly, N. Hawthorne, D. Yong, S. E. Sanso, N. Rezaee, J. L. Sevetson, S. T. Seiler, , D. Haussler

The paper develops an IoT architecture to control biological devices in experiments, enabling real-time monitoring and automation through a unified web interface.

bioRxiv · Jul 29, 2021 · PreprintBioengineering

Single-cell analyses of immune thrombocytopenic patients reveal multiorgan dissemination of high-affinity autoreactive plasma cells

P. Canales Herrerias, E. Crickx, M. Broketa, A. Sokal, G. Chenon, I. Azzaoui, A. Vandenberghe, A. Perima, B. Iannascoli, O. Richard-Le Goff, C. Castrillon, G. Mottet, D. Sterlin, A. Robbins, M. Michel, , P. Bruhns

This study identifies high-affinity autoreactive plasma cells in multiple organs of ITP patients, showing treatment resistance and suggesting therapy failure mechanisms.

bioRxiv · Jun 29, 2021 · PreprintImmunology

Electron Microscopy Analysis of hAPP-Induced Neurodegeneration in the Glomerular Network

A. Robbins, Katherine S. Lehmann, Li Bai, Leonardo Belluscio

This study uses electron microscopy to examine how hAPP expression affects glomerular connectivity and subcellular structures in mice, finding recovery after hAPP expression is turned off.

bioRxiv · Oct 16, 2018 · PreprintNeuroscience