Bone marrow AdipoQ-lineage progenitors are a major cellular source of M-CSF that dominates bone marrow macrophage development, osteoclastogenesis and bone mass
K. Inoue, Y. Xia, Y. Qin, J. X. Jiang, M. Greenblatt, B. Zhao
The paper identifies bone marrow AdipoQ-lineage progenitors as a major source of M-CSF, showing their critical role in macrophage development, osteoclastogenesis, and bone mass regulation.
bioRxiv · Jul 28, 2022Cell Biology