Animal Behavior & CognitionbioRxivPreprint
Amyloid-β seeding effects are dependent on the presence of knock-in genes in the AppNL-G-F mice.
S. G. Lacoursiere, D. Westaway, J. Safar…·R. J. Sutherland
This study seeds Aβ peptides into AppNL-G-F mice to assess their impact on cognition and pathology, finding effects depend on the presence of the humanized App gene and Aβ in the seed.
DOI 10.1101/2022.05.28.492382