Cell BiologybioRxivPreprint
MANF regulates unfolded protein response and neuronal survival through its ER-located receptor IRE1α
V. Kovaleva, L.-Y. Yu, L. Ivanova…·M. Saarma
This study identifies MANF's mechanism of action through its interaction with IRE1α, showing it modulates UPR and protects neurons from ER stress.
DOI 10.1101/2020.09.22.307744