Author

J. Huiskonen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Eesmaa· 1 shared C. Bulawa· 1 shared D. Tranter· 1 shared E. Pardon· 1 shared E.-P. Kumpula· 1 shared G. Chi· 1 shared H. Kramer· 1 shared J. J. Kelly· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Eesmaa

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2 papers

Recent·Most cited

Snapshots of actin and tubulin folding inside the TRiC chaperonin

J. J. Kelly, D. Tranter, E. Pardon, G. Chi, H. Kramer, K. Knee, J. Janz, J. Steyaert, C. Bulawa, V. Paavilainen, J. Huiskonen, W. Yue

The paper captures structural snapshots of actin and tubulin folding within the TRiC chaperonin using cryo-EM, revealing how substrates interact with the chamber during folding.

bioRxiv · Mar 26, 2021Biochemistry

MANF regulates unfolded protein response and neuronal survival through its ER-located receptor IRE1α

V. Kovaleva, L.-Y. Yu, L. Ivanova, J. Nam, A. Eesmaa, E.-P. Kumpula, J. Huiskonen, P. Lindholm, M. H. Voutilainen, M. Karelson, M. Saarma

This study identifies MANF's mechanism of action through its interaction with IRE1α, showing it modulates UPR and protects neurons from ER stress.

bioRxiv · Sep 22, 2020 · PreprintCell Biology