Author

M. H. Yang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

A. G. Stephen· 1 shared B. Hunt· 1 shared C. W. Johnson· 1 shared D. K. Simanshu· 1 shared J. A. Nowak· 1 shared K. M. Haigis· 1 shared R. Agnor· 1 shared T. H. Tran· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. G. Stephen

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1 paper

Recent·Most cited

Allosteric regulation of switch-II controls K-Ras oncogenicity

M. H. Yang, T. H. Tran, B. Hunt, R. Agnor, C. W. Johnson, T. J. Waybright, J. A. Nowak, A. G. Stephen, D. K. Simanshu, K. M. Haigis

This study shows that the K104Q mutation reduces oncogenic K-Ras activity in vivo by disrupting GEF-mediated nucleotide exchange and stabilizing switch-II helix through an allosteric network.

bioRxiv · Sep 20, 2022 · PreprintCancer Biology