Author

M. Holdorf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Organism:virus· 1

Frequent Co-Authors

A. Hyrina· 2 shared A. Frank· 1 shared A. Lindeman· 1 shared A. Proudfoot· 1 shared C. Jones· 1 shared C. Russ· 1 shared D. Bussiere· 1 shared D. Chen· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

A. Hyrina

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A genome-wide CRISPR screen identifies ZCCHC14 as a host factor required for hepatitis B surface antigen production

A. Hyrina, C. Jones, D. Chen, S. Clarkson, N. Cochran, P. Feucht, G. Hoffman, A. Lindeman, C. Russ, F. Sigoillot, K. Uehara, L. Xie, D. Ganem, M. Holdorf

The paper uses a genome-wide CRISPR screen to identify ZCCHC14 as a host factor required for hepatitis B surface antigen production and shows it stabilizes HBsAg through RNA tailing with TENT4A/B.

bioRxiv · Jul 30, 2019Microbiology

First Crystal Structure of a Non-Structural Hepatitis E Viral Protein Identifies a Putative Novel Zinc-Binding Protein

A. Proudfoot, A. Hyrina, M. Holdorf, A. Frank, D. Bussiere

The paper determines the crystal structure of a non-structural HEV protein, revealing a zinc-binding motif and structural homology to a fatty acid binding domain.

bioRxiv · Feb 2, 2019Biophysics