An ancient transcription activator is required for the multiciliogenesis program
H. Jiang, M. Hua, M. Ding, J. Hu, S. Zheng, H. Wang, W. Wang, c. xu, J. Xing, H. Liu, X. Zhao, Z. Hu
This study identifies Edf1 as an essential transcription activator for multiciliogenesis, showing its role in ciliary gene expression and its impact on hydrocephalus in mice.
bioRxiv · Dec 16, 2023 · PreprintCell Biology