Targeting extracellular glycans: Tuning multimeric boronic acids for pathogen-selective killing of Mycobacterium tuberculosis
C. S. Guy, M. I. Gibson, E. Fullam
This study designs multimeric boronic acids that selectively kill Mycobacterium tuberculosis by targeting its unique extracellular glycans, achieving high selectivity and low cytotoxicity.
bioRxiv · Jan 24, 2019Biochemistry