ImmunologybioRxivPreprint
Ebola Virus VP35 Interacts Non-Covalently with Ubiquitin Chains to Promote Viral Replication Creating New Therapeutic Opportunities
C. A. Rodriguez-Salazar, S. van Tol, O. Mailhot…·R. Rajsbaum
This study identifies a non-covalent interaction between Ebola virus VP35 and ubiquitin chains that supports viral replication and discovers compounds that block this interaction to reduce viral activity.
DOI 10.1101/2023.07.14.549057