Author

S. van Tol

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. N. Freiberg· 2 shared R. Rajsbaum· 2 shared A. Carmody· 1 shared A. Marzi· 1 shared A. Meijer· 1 shared A. N. Warren· 1 shared A. Okumura· 1 shared B. J. Smith· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

A. N. Freiberg

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Author profile →

4 papers

Recent·Most cited

A bivalent Adenovirus-Vectored Vaccine induces a measurable humoral response, but does not protect cynomolgus macaques against a lethal challenge with Sudan virus

S. van Tol, P. Fletcher, F. Feldmann, R. K. Mukesh, J. R. Port, S. Gallogly, J. E. Schulz, J. F. Roderick, R. Makinson, A. Carmody, L. Myers, J. Lovaglio, B. J. Smith, A. Okumura, C. Shaia, , N. van Doremalen

This study evaluates a bivalent Adenovirus-Vectored Vaccine in cynomolgus macaques against Sudan virus, finding it induces humoral responses but does not confer protection against lethal challenge.

bioRxiv · Oct 20, 2023Microbiology

Ebola Virus VP35 Interacts Non-Covalently with Ubiquitin Chains to Promote Viral Replication Creating New Therapeutic Opportunities

C. A. Rodriguez-Salazar, S. van Tol, O. Mailhot, G. T. Galdino, N. F. Borges Teruel, L. Zhang, A. N. Warren, M. Gonzalez-Orozco, A. N. Freiberg, R. J. Najmanovich, M. I. Giraldo, R. Rajsbaum

This study identifies a non-covalent interaction between Ebola virus VP35 and ubiquitin chains that supports viral replication and discovers compounds that block this interaction to reduce viral activity.

bioRxiv · Jul 14, 2023 · PreprintImmunology

The Consequences of Egg Adaptation in the H3N2 Component to the Immunogenicity of Live Attenuated Influenza Vaccine

D. H. Goldhill, B. Lindsey, R. Kugathasan, Z. F. Garza, Y. J. Jagne, H. J. Sallah, G. Goderski, S. van Tol, K. Höschler, A. Meijer, W. S. Barclay, T. de Silva

This study examines how egg adaptation of the H3N2 influenza vaccine strain affects antibody responses in children, finding higher seroconversion rates to the adapted strain but differential mucosal IgA responses based on prior serostatus.

bioRxiv · Nov 12, 2019 · PreprintImmunology

VAMP8 contributes to TRIM6-mediated type-I interferon antiviral response during West Nile virus infection

C. Atkins, S. Van Tol, P. Bharaj, R. Rajsbaum, A. N. Freiberg

This paper identifies VAMP8 as a novel gene regulated by TRIM6 that enhances IFN-I signaling and restricts WNV replication in human cells.

bioRxiv · Dec 1, 2018Immunology