A novel microRNA-based strategy to expand the differentiation potency of stem cells
M. Salazar-Roa, M. Trakala, M. Alvarez-Fernandez, F. Valdes-Mora, C. Zhong, J. Munoz, Y. Yu, T. J. Peters, O. Grana Castro, R. Serrano, E. Zapatero-Solana, M. Abad, M. J. Bueno, M. Gomez de Cedron, J. Fernandez-Piqueras, , M. Malumbres
This study shows that transient exposure to miR-203 enhances the differentiation capacity of murine and human PSCs by reversing DNA methylation.
bioRxiv · Nov 4, 2019Cell Biology