Author

M. J. Loessner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:bacteria (other)· 3 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:metagenomics· 2

Frequent Co-Authors

S. Kilcher· 4 shared J. Baggenstos· 3 shared C. I. Matter· 2 shared J. Du· 2 shared L. Hunold· 2 shared L. Leitner· 2 shared M. Dunne· 2 shared P. Piffaretti· 2 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersBioengineering

S. Kilcher

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

CRISPR-Cas9 enables efficient genome engineering of the strictly lytic, broad host-range staphylococcal bacteriophage K

J. Fernbach, J. Baggenstos, J. Riedo, S. McCallin, M. J. Loessner, S. Kilcher

This paper develops a CRISPR-Cas9-based platform for engineering Twortvirinae phages to create reporter phages for detecting Staphylococcus aureus in clinical and environmental samples.

bioRxiv · Mar 19, 2024Bioengineering

Engineered reporter phages for rapid detection of Escherichia coli, Klebsiella spp., and Enterococcus spp. in urine

S. Meile, J. Du, S. Staubli, S. Grossmann, H. Koliwer-Brandl, P. Piffaretti, L. Leitner, C. I. Matter, J. Baggenstos, L. Hunold, S. Milek, C. Guebeli, M. Kozomara-Hocke, V. Neumeier, A. Botteon, , S. Kilcher

This study develops a rapid phage-based diagnostic assay to detect E. coli, Klebsiella spp., and Enterococcus spp. in urine with high sensitivity and specificity within 5 hours.

bioRxiv · Nov 23, 2022 · PreprintMicrobiology

Gram-positive bacteria evade phage predation through endolysin-mediated L-form conversion

J. C. Wohlfarth, M. Feldmueller, A. Schneller, S. Kilcher, M. Burkolter, M. Pilhofer, M. Schuppler, M. J. Loessner

This paper shows Gram-positive bacteria like Listeria monocytogenes and Enterococcus faecalis can evade phage predation by temporarily converting to L-forms, which are wall-deficient but viable cells.

bioRxiv · May 24, 2022 · PreprintMicrobiology

Enhancing bacteriophage therapeutics through in situ production and release of heterologous antimicrobial effectors

J. Du, S. Meile, J. Baggenstos, T. Jaeggi, P. Piffaretti, L. Hunold, C. I. Matter, L. Leitner, T. M. Kessler, M. J. Loessner, S. Kilcher, M. Dunne

This paper develops heterologous effector phage therapeutics (HEPTs) to enhance bacteriophage treatment of UTIs by delivering colicin-like effectors that suppress resistance and improve bacterial killing.

bioRxiv · Mar 9, 2022 · PreprintBioengineering

Glucose decoration on wall-teichoic acid is required for phage adsorption and InlB-mediated virulence in Listeria ivanovii

E. T. Sumrall, S. R. Schneider, S. Boulos, M. J. Loessner, Y. Shen

bioRxiv · Mar 8, 2021Microbiology

Bacillus subtilis YngB contributes to wall teichoic acid glucosylation and glycolipid formation during anaerobic growth

C.-H. Wu, J. Rismondo, R. M. L. Morgan, Y. Shen, M. J. Loessner, G. Larrouy-Maumus, P. S. Freemont, A. Grundling

This study identifies YngB as a UGPase in B. subtilis that contributes to WTA glucosylation and glycolipid formation under anaerobic conditions.

bioRxiv · Nov 30, 2020 · PreprintMicrobiology

Uncovering a hidden diversity: optimized protocols for the extraction of bacteriophages from soil

P. C. Goeller, J. M. Haro-Moreno, F. Rodriguez-Valera, M. J. Loessner, E. Gomez-Sanz

This paper optimizes protocols for extracting bacteriophages from soil, improving phage recovery and reducing bacterial contamination, and discovers novel phage genomes.

bioRxiv · Aug 15, 2019Microbiology