Author

M. J. Metzger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 4 Approach:experimental assay· 3 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:ecology & biodiversity· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

M. A. Yonemitsu· 4 shared R. M. Giersch· 3 shared E. Unsell· 2 shared L. E. Vandepas· 2 shared R. N. Crim· 2 shared S. F. Hart· 2 shared A. Benabdelmouna· 1 shared A. Lacy-Hulbert· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersCancer Biology

M. A. Yonemitsu

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Author profile →

5 papers

Recent·Most cited

Multiple lineages of transmissible neoplasia in the basket cockle (Clinocardium nuttallii) with repeated horizontal transfer of mitochondrial DNA

M. A. Yonemitsu, J. K. Sevigny, L. E. Vandepas, J. L. Dimond, R. M. Giersch, H. J. Gurney-Smith, C. L. Abbott, J. Supernault, R. Withler, P. D. Smith, S. A. Weinandt, F. E. Garrett, Z. J. Child, R. L. Sigo, E. Unsell, , M. J. Metzger

The paper identifies two lineages of transmissible neoplasia in basket cockles, with one lineage showing repeated horizontal transfer of mitochondrial DNA.

bioRxiv · Oct 11, 2023Cancer Biology

A rapid, inexpensive, non-lethal method for detecting disseminated neoplasia in a bivalve

L. E. Vandepas, R. N. Crim, E. Gilbertson, M. A. Yonemitsu, E. Unsell, M. J. Metzger, A. Lacy-Hulbert, F. W. Goetz

This paper presents a non-lethal, rapid, and low-cost method for detecting disseminated neoplasia in basket cockles, validated against histology with high accuracy.

bioRxiv · Jun 28, 2023 · PreprintCell Biology

Centuries of genome instability and evolution in soft-shell clam transmissible cancer

S. F. Hart, M. A. Yonemitsu, R. M. Giersch, B. F. Beal, G. Arriagada, B. W. Davis, E. A. Ostrander, S. P. Goff, M. J. Metzger

The paper analyzes the genome of a transmissible cancer in soft-shell clams to show its long evolutionary history and structural genomic instability over ~500 years.

bioRxiv · Aug 7, 2022Cancer Biology

Survival and detection of bivalve transmissible neoplasia from the soft-shell clam Mya arenaria (MarBTN) in seawater

R. M. Giersch, S. F. Hart, S. G. Reddy, M. A. Yonemitsu, M. J. Orellana Rosales, M. Korn, B. M. Geleta, P. D. Countway, J. A. Fernandez Robledo, M. J. Metzger

This study tests whether bivalve transmissible neoplasia (BTN) cells can survive in seawater and be released into the environment, supporting a waterborne transmission mechanism.

bioRxiv · Dec 25, 2021Cancer Biology

Prevalence and polymorphism of a mussel transmissible cancer in Europe

M. Hammel, A. Simon, C. Arbiol, A. Villalba, E. A. V. Burioli, J.-F. Pepin, J.-B. Lamy, A. Benabdelmouna, I. Bernard, M. Houssin, G. M. Charriere, D. Destoumieux-Garzon, J. Welch, M. J. Metzger, N. Bierne

The paper screens European mussels for transmissible cancer lineages, finding low prevalence of MtrBTN2 and polymorphism suggesting complex diversification.

bioRxiv · Mar 31, 2021Evolutionary Biology