Author

S. F. Hart

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Organism:yeast· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:ecology & biodiversity· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. A. Yonemitsu· 2 shared M. J. Metzger· 2 shared R. Green· 2 shared R. M. Giersch· 2 shared W. Shou· 2 shared A. Capel· 1 shared A. Lin· 1 shared A. R. Subramaniam· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

M. A. Yonemitsu

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Author profile →

4 papers

Recent·Most cited

Centuries of genome instability and evolution in soft-shell clam transmissible cancer

S. F. Hart, M. A. Yonemitsu, R. M. Giersch, B. F. Beal, G. Arriagada, B. W. Davis, E. A. Ostrander, S. P. Goff, M. J. Metzger

The paper analyzes the genome of a transmissible cancer in soft-shell clams to show its long evolutionary history and structural genomic instability over ~500 years.

bioRxiv · Aug 7, 2022Cancer Biology

Survival and detection of bivalve transmissible neoplasia from the soft-shell clam Mya arenaria (MarBTN) in seawater

R. M. Giersch, S. F. Hart, S. G. Reddy, M. A. Yonemitsu, M. J. Orellana Rosales, M. Korn, B. M. Geleta, P. D. Countway, J. A. Fernandez Robledo, M. J. Metzger

This study tests whether bivalve transmissible neoplasia (BTN) cells can survive in seawater and be released into the environment, supporting a waterborne transmission mechanism.

bioRxiv · Dec 25, 2021Cancer Biology

Metabolic excretion associated with nutrient-growth dysregulation promotes the rapid evolution of an overt metabolic defect

R. Green, S. Sonal, W. Lu, L. Wang, S. F. Hart, D. Skelding, J. C. Burton, A. Capel, H. A. Chen, A. Lin, A. R. Subramaniam, J. D. Rabinowitz, W. Shou

The paper shows that nutrient-growth dysregulation in yeast leads to the evolution of a metabolic defect involving organosulfur release, which confers a fitness advantage under specific conditions.

bioRxiv · Apr 26, 2020Evolutionary Biology

Disentangling strictly self-serving mutations from win-win mutations in a mutualistic microbial community

S. F. Hart, J. M. B. Pineda, C.-C. Chen, R. Green, W. Shou

The paper shows that a mutation increasing hypoxanthine release in yeast was mistakenly thought to be win-win but is actually self-serving due to increased cell size and lysine consumption.

bioRxiv · Mar 16, 2019Microbiology