Excess crossovers impede faithful meiotic chromosome segregation in C. elegans
J. A. Hollis, M. L. Glover, A. Schlientz, C. K. Cahoon, B. Bowerman, S. M. Wignall, D. E. Libuda
This study shows that excess crossovers in C. elegans cause chromosome mispatterning and segregation defects, but these errors are corrected by LEM-3 nuclease and homolog tethers during meiosis.
bioRxiv · Jan 30, 2020Cell Biology