Sorting for CCR7-positivity enriches for a dendritic cell population with enhanced antigen-presenting capacity and anti-tumour potency
P. Burgoyne, A. J. Hayes, R. S. Cooper, M. L. Le Brocq, C. A. H. Hansell, J. D. M. Campbell, G. J. Graham
This study shows that selecting dendritic cells with high CCR7 expression improves their ability to migrate to lymph nodes and enhance anti-tumour immune responses in melanoma models.
bioRxiv · Sep 4, 2019 · PreprintImmunology